Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Malignant refers to the characteristic of cancer cells that are invasive and capable of spreading to other parts of the body. Unlike benign tumors, malignant cells can metastasize and often lead to serious health issues.
5 Must Know Facts For Your Next Test
Malignant tumors are often aggressive and can invade nearby tissues.
Metastasis is a hallmark of malignancy, where cancer cells spread through the bloodstream or lymphatic system.
Malignant cells often evade the immune system, making them harder to target with immunotherapy.
Genetic mutations and alterations in tumor suppressor genes contribute to malignant transformation.
Treatment for malignant cancers may involve surgery, radiation therapy, chemotherapy, and immunotherapy.
Review Questions
Related terms
Benign: A term used to describe non-cancerous tumors that do not invade surrounding tissues or metastasize.
Metastasis: The process by which cancer cells spread from the primary site to other parts of the body.
Tumor Suppressor Genes: Genes that help regulate cell growth and prevent uncontrolled cell proliferation; their mutation can lead to cancer.