M protein is a virulence factor found on the surface of certain bacteria, notably Streptococcus pyogenes. It plays a crucial role in evading the host immune response by inhibiting phagocytosis.
5 Must Know Facts For Your Next Test
M protein contributes to the pathogenicity of Streptococcus pyogenes by preventing opsonization.
The gene encoding M protein is highly variable, leading to numerous serotypes.
M protein can bind to fibrinogen and complement regulatory proteins, enhancing bacterial survival.
Laboratory detection of M protein can be critical for diagnosing streptococcal infections.
Vaccines targeting M protein are being researched as potential preventive measures against streptococcal diseases.