🦠microbiology review

LUCA

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

LUCA stands for Last Universal Common Ancestor, the most recent population of organisms from which all organisms now living on Earth have a common descent. LUCA is not a specific organism but rather a concept used to trace the evolutionary history of life.

5 Must Know Facts For Your Next Test

  1. LUCA existed around 3.5 to 3.8 billion years ago.
  2. It is believed that LUCA was a prokaryotic organism.
  3. LUCA likely had a simple cell structure without a nucleus or membrane-bound organelles.
  4. Genetic evidence suggests LUCA had DNA, RNA, and proteins as part of its molecular machinery.
  5. LUCA's metabolism might have been similar to modern deeply branching bacteria found in extreme environments.

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