Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Loiasis is a parasitic infection caused by the filarial nematode Loa loa, commonly known as the African eye worm. It primarily affects the skin and eyes of humans.
5 Must Know Facts For Your Next Test
Loiasis is transmitted to humans through the bite of an infected deerfly (Chrysops species).
Patients with loiasis often experience Calabar swellings, which are localized subcutaneous swellings.
The adult Loa loa worms can migrate across the eye, which can be visibly observed and cause significant discomfort.
Diagnosis often involves identifying microfilariae in blood samples, especially during daytime when their presence peaks.
Treatment typically includes antiparasitic medications such as diethylcarbamazine (DEC) or ivermectin.
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Related terms
Onchocerciasis: A parasitic disease caused by Onchocerca volvulus, also known as river blindness.
Filariasis: A group of tropical diseases caused by thread-like filarial nematodes.