Live attenuated vaccine

Definition

A live attenuated vaccine uses a weakened form of the virus, which can still replicate but does not cause disease. It stimulates a strong immune response by mimicking a natural infection.

5 Must Know Facts For Your Next Test

1. Live attenuated vaccines are often used against viral infections like measles, mumps, and rubella.
2. They generally provide long-lasting immunity with fewer doses compared to inactivated vaccines.
3. These vaccines require careful storage at low temperatures to maintain their efficacy.
4. Individuals with compromised immune systems should avoid live attenuated vaccines due to the risk of disease.
5. Common examples include the MMR (measles, mumps, rubella) vaccine and the intranasal influenza vaccine.

Review Questions

• What is the primary advantage of live attenuated vaccines over inactivated vaccines?
• Why must live attenuated vaccines be stored at low temperatures?
• Name two respiratory illnesses that can be prevented using live attenuated vaccines.

Related terms

Inactivated Vaccine:

A type of vaccine made from viruses or bacteria that have been killed through physical or chemical processes.

Immunocompromised:

Having an impaired or weakened immune system, making one more vulnerable to infections.

MMR Vaccine:

A combined vaccine that protects against measles, mumps, and rubella using live attenuated viruses.