🦠microbiology review

Leptospirosis

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Leptospirosis is a bacterial infection caused by Leptospira species, primarily affecting the kidneys and urinary system. It is commonly transmitted through contact with water contaminated by the urine of infected animals.

5 Must Know Facts For Your Next Test

  1. Leptospirosis can lead to severe kidney damage and even renal failure if left untreated.
  2. Humans typically contract leptospirosis through direct contact with contaminated water or soil.
  3. Symptoms of leptospirosis include high fever, headache, muscle aches, jaundice, and vomiting.
  4. The disease is diagnosed through serological tests such as the Microscopic Agglutination Test (MAT).
  5. Antibiotics like doxycycline or penicillin are commonly used to treat leptospirosis.

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