Lambda

Definition

Lambda is a bacteriophage, a virus that infects bacteria, specifically E. coli. It is widely used in genetic engineering due to its ability to integrate into the host genome.

5 Must Know Facts For Your Next Test

1. Lambda phage can exist in two states: lytic and lysogenic cycles.
2. In the lytic cycle, lambda phage replicates quickly and causes cell lysis.
3. In the lysogenic cycle, lambda DNA integrates into the host genome and replicates along with it.
4. Lambda phage is commonly used as a vector for cloning genes in genetic engineering.
5. The lambda red recombination system is crucial for making precise genetic modifications.

Review Questions

• What are the two life cycles of lambda phage?
• How does lambda phage integrate into the host genome?
• Why is lambda phage considered an important tool in genetic engineering?

Related terms

Bacteriophage:

A virus that infects and replicates within bacteria.

Lytic Cycle:

A process where a virus replicates within a host cell and eventually causes cell lysis.

Lysogenic Cycle:

A viral replication process where the virus integrates its DNA into the host cell's genome.