🦠microbiology review

Lag period

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

The lag period is the initial phase after exposure to an antigen during which no antibodies are detectable in the blood. This period allows for the activation and proliferation of specific B lymphocytes.

5 Must Know Facts For Your Next Test

  1. The lag period typically lasts between 3-6 days.
  2. During the lag period, antigen-presenting cells process and present antigens to helper T cells.
  3. B lymphocytes undergo clonal expansion and differentiation into plasma cells during this time.
  4. The length of the lag period can be influenced by factors such as the nature of the antigen and previous exposures.
  5. The lag period is followed by the log phase, where there is a rapid increase in antibody production.

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