Koplik’s spots Definition - Microbiology Key Term

Definition

Koplik's spots are small, white lesions with a bluish center found on the buccal mucosa. They are a pathognomonic sign of measles infection.

Koplik's spots usually appear 1-2 days before the measles rash.
They are typically found opposite the molars inside the mouth.
These spots are caused by viral replication and immune response in the mucosal tissues.
Their presence strongly indicates an active measles infection, even before other symptoms appear.
Koplik's spots are often described as 'grains of salt on a red background.'

A highly contagious virus that causes fever, cough, conjunctivitis, and a characteristic rash.

Buccal Mucosa: The inner lining of the cheeks where Koplik's spots can be observed.

Pathognomonic Sign: A sign or symptom specifically characteristic or indicative of a particular disease condition.