Keratin

Definition

Keratin is a fibrous structural protein found in the outer layer of the skin, as well as in hair and nails. It provides protection and strength to epithelial cells against damage or stress.

5 Must Know Facts For Your Next Test

1. Keratin helps protect skin from physical damage and microbial invasion.
2. It is produced by keratinocytes, which are the predominant cell type in the epidermis.
3. Keratin forms a barrier that prevents pathogens from entering through the skin.
4. Mutations or deficiencies in keratin can lead to skin disorders such as ichthyosis vulgaris.
5. The protein plays a role in wound healing by providing structural support.

Review Questions

• What type of cells primarily produce keratin?
• How does keratin contribute to the skin's defense against pathogens?
• What are some potential consequences of keratin deficiencies or mutations?

Related terms

Epidermis: The outermost layer of the skin where keratinocytes are located.

Keratinocyte: A type of cell that produces keratin and makes up most of the epidermis.

Ichthyosis Vulgaris: A skin disorder caused by mutations affecting keratin production, leading to dry, scaly skin.