🦠microbiology review
key term - Ivermectin
Definition
Ivermectin is an antiparasitic drug used to treat various helminthic infections. It works by binding to glutamate-gated chloride channels in the parasite's nerve and muscle cells, causing paralysis and death of the parasite.
5 Must Know Facts For Your Next Test
- Ivermectin is effective against a range of parasitic worms, including those causing onchocerciasis and strongyloidiasis.
- It is also used to treat ectoparasitic infections like scabies and head lice.
- The drug has a high safety profile but should be used cautiously in people with compromised blood-brain barriers.
- Ivermectin is derived from avermectins, which are naturally occurring compounds produced by the bacterium Streptomyces avermitilis.
- Resistance to ivermectin can develop in parasites, necessitating combination therapies or alternative treatments.