🦠microbiology review

Invasion factors

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Invasion factors are molecules produced by pathogens that facilitate their entry and spread within a host organism. These factors enable the pathogen to breach host barriers, evade immune responses, and establish infection.

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5 Must Know Facts For Your Next Test

  1. Invasion factors include enzymes like hyaluronidase and collagenase that degrade host tissues.
  2. Some bacteria use pili or fimbriae as invasion factors to adhere to and penetrate host cells.
  3. Invasion factors can manipulate host cell signaling pathways to promote bacterial uptake.
  4. Capsules and surface proteins are also invasion factors that help bacteria avoid phagocytosis.
  5. The production of invasion factors is often regulated by quorum sensing in bacterial populations.

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