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Inactivated vaccines

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Inactivated vaccines are made from viruses or bacteria that have been killed through physical or chemical processes. These vaccines cannot cause disease but still stimulate an immune response.

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5 Must Know Facts For Your Next Test

  1. Inactivated vaccines often require multiple doses to achieve and maintain immunity.
  2. They are generally stable and safer than live vaccines, especially for immunocompromised individuals.
  3. Common examples include the polio (IPV), hepatitis A, and rabies vaccines.
  4. Booster shots may be necessary to ensure long-term immunity since the immune response is not as strong as with live vaccines.
  5. Inactivated pathogens in these vaccines retain their surface antigens, which are crucial for inducing an immune response.

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