Hyperpigmentation

Definition

Hyperpigmentation is the darkening of an area of skin caused by increased melanin production. It can be triggered by various factors, including autoimmune disorders.

5 Must Know Facts For Your Next Test

1. Hyperpigmentation can be a symptom of autoimmune disorders like systemic lupus erythematosus (SLE).
2. In autoimmune diseases, hyperpigmentation occurs due to inflammatory processes and immune-mediated damage.
3. Certain medications used to treat autoimmune conditions can also cause hyperpigmentation as a side effect.
4. Diagnosis often involves assessing clinical history and may require biopsies or lab tests to identify underlying autoimmune causes.
5. Treatment approaches may include topical agents, laser therapy, and addressing the underlying autoimmune disorder.

Review Questions

• What is the role of melanin in hyperpigmentation?
• How can autoimmune disorders contribute to hyperpigmentation?
• What are common treatment options for hyperpigmentation associated with autoimmune diseases?

Related terms

Melanin:

A pigment produced by melanocytes that gives color to the skin.

Systemic Lupus Erythematosus (SLE): An autoimmune disease characterized by chronic inflammation affecting multiple organs.

Inflammation:

The body's response to injury or infection, often causing redness, heat, swelling, and pain.