🦠microbiology review

Human herpesvirus

Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025

Definition

Human herpesvirus (HHV) is a group of DNA viruses responsible for causing various infections in humans, including those affecting the skin and eyes. These viruses are characterized by their ability to establish latent infections and reactivate later.

5 Must Know Facts For Your Next Test

  1. There are eight types of human herpesviruses, including HSV-1 and HSV-2 which are commonly associated with oral and genital lesions.
  2. Varicella-zoster virus (HHV-3) causes both chickenpox and shingles.
  3. Human herpesvirus is capable of latency, meaning it can remain dormant in nerve cells and reactivate under certain conditions.
  4. Herpes simplex virus (HSV) can cause keratitis, an infection of the cornea that may lead to blindness if untreated.
  5. Diagnosis often involves PCR (polymerase chain reaction) testing or viral culture from lesions.
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