Human growth hormone

Definition

Human growth hormone (HGH) is a peptide hormone that stimulates growth, cell reproduction, and regeneration in humans. It is produced by the pituitary gland and has significant applications in medicine and genetic engineering.

5 Must Know Facts For Your Next Test

1. Recombinant DNA technology allows for the production of synthetic HGH using microbial systems like E. coli.
2. HGH therapy can be used to treat growth disorders in children and growth hormone deficiency in adults.
3. Genetically engineered microbes can produce large quantities of HGH, making it more accessible for therapeutic use.
4. Whole genome sequencing methods are utilized to identify genes involved in HGH regulation and production.
5. Pharmaceutical applications of genetically engineered HGH include treatments for muscle wasting diseases and certain types of dwarfism.

Review Questions

• How is recombinant DNA technology used to produce synthetic human growth hormone?
• What are some medical conditions that can be treated with HGH therapy?
• How do whole genome sequencing methods contribute to the understanding of HGH regulation?

Related terms

Recombinant DNA Technology: A method used to join together DNA from different sources to create new genetic combinations.

E. coli:

A common bacterium often used as a host organism in genetic engineering.

Gene Regulation: The process of turning genes on or off to control cellular function and differentiation.