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HIV infection

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

HIV infection is caused by the human immunodeficiency virus, which attacks and weakens the immune system, specifically targeting CD4+ T cells. If untreated, it can progress to AIDS (Acquired Immunodeficiency Syndrome), a severe condition where the immune system is heavily compromised.

5 Must Know Facts For Your Next Test

  1. HIV primarily targets and destroys CD4+ T cells, leading to immunodeficiency.
  2. Transmission of HIV occurs through bodily fluids such as blood, semen, vaginal fluids, and breast milk.
  3. The progression of HIV infection can be categorized into three stages: acute infection, clinical latency, and AIDS.
  4. Antiretroviral therapy (ART) is used to manage HIV infection by reducing viral load and improving immune function.
  5. HIV can be diagnosed through various tests including ELISA, Western blot, and PCR for detecting viral RNA.

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