Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
HIV (Human Immunodeficiency Virus) is a virus that targets the immune system, specifically CD4 cells (T cells), leading to a progressive failure of the immune system. If left untreated, HIV can lead to AIDS (Acquired Immunodeficiency Syndrome).
5 Must Know Facts For Your Next Test
HIV primarily infects CD4+ T cells, macrophages, and dendritic cells.
The virus uses reverse transcriptase to convert its RNA into DNA within the host cell.
HIV transmission occurs through bodily fluids such as blood, semen, vaginal fluids, and breast milk.
Antiretroviral therapy (ART) can effectively control HIV replication and prevent the progression to AIDS.
ELISA and Western blot tests are commonly used for diagnosing HIV infection.
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Related terms
CD4 Cells: Immune cells targeted by HIV; crucial for immune system function.