🦠microbiology review

HDV

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

HDV, or Hepatitis D Virus, is a defective virus that requires the presence of Hepatitis B Virus (HBV) to replicate. It primarily affects the liver and can exacerbate HBV infections.

5 Must Know Facts For Your Next Test

  1. HDV co-infection with HBV can result in more severe liver disease than HBV infection alone.
  2. The transmission of HDV occurs via blood or body fluids, similar to HBV.
  3. Vaccination against HBV can effectively prevent HDV infection since HDV requires HBV for replication.
  4. Symptoms of HDV infection include jaundice, abdominal pain, nausea, and fatigue.
  5. Diagnosis of HDV involves detecting HDV RNA or anti-HDV antibodies in the blood.

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