Griseofulvin

Definition

Griseofulvin is an antifungal medication used to treat fungal infections of the skin, hair, and nails. It works by inhibiting fungal cell mitosis, leading to the disruption of fungal growth.

5 Must Know Facts For Your Next Test

1. Griseofulvin targets dermatophytes, which are fungi that cause infections in keratinized tissues.
2. It binds to keratin in human cells, making them resistant to fungal invasion.
3. The drug is typically administered orally and requires prolonged treatment courses, often several weeks or months.
4. Common side effects include headache, gastrointestinal upset, and photosensitivity.
5. Griseofulvin is metabolized by the liver and can interact with other medications by inducing hepatic enzymes.

Review Questions

Related terms

Dermatophytes: A group of fungi that cause infections in skin, hair, and nails.

Antifungal Agents:

Medications used to treat fungal infections.

Photosensitivity: Increased sensitivity to sunlight, a possible side effect of certain medications like griseofulvin.