Glomerulus

Definition

The glomerulus is a network of capillaries located at the beginning of a nephron in the kidney. It plays a crucial role in the filtration of blood to form urine.

5 Must Know Facts For Your Next Test

1. The glomerulus filters blood plasma to initiate urine formation.
2. It is part of the renal corpuscle, along with Bowman's capsule.
3. Diseases affecting the glomerulus can lead to conditions such as glomerulonephritis.
4. The filtration barrier in the glomerulus includes endothelial cells, a basement membrane, and podocytes.
5. Glomerular filtration rate (GFR) is an important measure of kidney function.

Review Questions

• What role does the glomerulus play in urine formation?
• Name two conditions that can result from diseases affecting the glomerulus.
• What are the components of the filtration barrier in the glomerulus?

Related terms

Nephron: The functional unit of the kidney responsible for forming urine.

Bowman's Capsule: A cup-like sac at the beginning of a nephron that encloses the glomerulus.

Glomerulonephritis: Inflammation of the tiny filters in your kidneys (glomeruli).