Ghon complexes

Definition

Ghon complexes are lesions found in the lungs of individuals infected with Mycobacterium tuberculosis. They consist of a calcified focus of infection and an associated lymph node.

5 Must Know Facts For Your Next Test

1. 1. Ghon complexes are characteristic findings in primary tuberculosis (TB).
2. 2. They typically form within the first few weeks after infection with Mycobacterium tuberculosis.
3. 3. A Ghon complex is composed of a Ghon focus, which is the initial site of infection, and a calcified regional lymph node.
4. 4. These complexes can be identified on chest X-rays as calcified nodules.
5. 5. The presence of a Ghon complex indicates prior exposure to TB, but it does not necessarily mean active disease.

Review Questions

• What organisms cause the formation of Ghon complexes?
• What components make up a Ghon complex?
• How can Ghon complexes be detected in patients?

Related terms

Mycobacterium tuberculosis: The bacterium that causes tuberculosis.

Ghon focus: The initial site of infection in the lung by Mycobacterium tuberculosis.

Primary Tuberculosis: The initial infection stage caused by Mycobacterium tuberculosis, often characterized by the formation of Ghon complexes.