Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
The fluid mosaic model describes the structure of cell membranes as a dynamic and flexible arrangement of lipids, proteins, and carbohydrates. This model emphasizes the lateral movement of components within the lipid bilayer.
5 Must Know Facts For Your Next Test
The fluid mosaic model was proposed by S.J. Singer and G.L. Nicolson in 1972.
Cell membranes are primarily composed of a phospholipid bilayer with embedded proteins.
Lipid molecules can move laterally within the bilayer, providing membrane fluidity.
Membrane proteins can be integral (spanning the bilayer) or peripheral (attached to the surface).
Cholesterol within the membrane helps modulate its fluidity and stability.
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Related terms
Phospholipid Bilayer: A double layer of phospholipids that forms the fundamental structure of cell membranes.
Integral Proteins: Proteins that span across the lipid bilayer, often involved in transport and signaling.
Peripheral Proteins: Proteins attached to either side of the lipid bilayer, typically playing roles in signaling or maintaining cell shape.