🦠microbiology review

F plasmid

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

The F plasmid, or fertility plasmid, is a circular piece of DNA that enables bacteria to transfer genetic material through conjugation. It contains genes that code for the formation of a pilus and other proteins essential for this process.

5 Must Know Facts For Your Next Test

  1. F plasmids facilitate horizontal gene transfer between bacterial cells via conjugation.
  2. They contain tra genes that encode proteins necessary for pilus formation.
  3. F+ cells possess the F plasmid, while F- cells do not.
  4. During conjugation, the F plasmid can be transferred from an F+ cell to an F- cell, converting it into an F+ cell.
  5. The integration of the F plasmid into the bacterial chromosome can lead to high-frequency recombination (Hfr) strains.

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