🦠microbiology review

Exotoxins

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Exotoxins are toxic proteins secreted by certain bacteria that can cause damage to the host by destroying cells or disrupting normal cellular metabolism. They are typically associated with specific symptoms in infections of the gastrointestinal tract.

5 Must Know Facts For Your Next Test

  1. Exotoxins can be produced by both Gram-positive and Gram-negative bacteria.
  2. Cholera toxin, produced by Vibrio cholerae, is a well-known exotoxin that causes severe diarrhea.
  3. Exotoxins are often heat-labile, meaning they can be deactivated by heating.
  4. These toxins are highly potent and can act at very low concentrations.
  5. Exotoxins can be categorized into three main types: cytotoxins, neurotoxins, and enterotoxins.

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