Epstein-Barr virus
from class: Microbiology Definition Epstein-Barr virus (EBV) is a herpesvirus that primarily infects B cells and epithelial cells, causing mononucleosis. It is associated with several cancers, including Burkitt's lymphoma and nasopharyngeal carcinoma.
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Predict what's on your test 5 Must Know Facts For Your Next Test EBV is transmitted through saliva, often referred to as the 'kissing disease'. Primary infection usually results in infectious mononucleosis, characterized by fever, sore throat, and swollen lymph nodes. EBV establishes latent infection in B lymphocytes, which can lead to reactivation under certain conditions. Diagnosis of EBV infection can be confirmed using serological tests for specific antibodies such as VCA-IgM and EBNA. There is no specific antiviral treatment for EBV; management focuses on symptomatic relief. Review Questions What are the primary cells infected by Epstein-Barr virus? How is Epstein-Barr virus typically transmitted? What are common symptoms of infectious mononucleosis caused by EBV? "Epstein-Barr virus" also found in:
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