🦠microbiology review

Epidemic typhus

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Epidemic typhus is a bacterial infection caused by Rickettsia prowazekii, primarily transmitted through the body louse. Characterized by high fever, rash, and severe headache, it can be fatal if untreated.

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5 Must Know Facts For Your Next Test

  1. Epidemic typhus is caused by the bacterium Rickettsia prowazekii.
  2. The primary vector for transmission is the human body louse (Pediculus humanus corporis).
  3. Symptoms include high fever, chills, rash, and severe headache.
  4. Infection can lead to serious complications such as myocarditis, encephalitis, and death if not treated promptly.
  5. Tetracycline antibiotics like doxycycline are effective in treating epidemic typhus.

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