Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Enteropathogenic Escherichia coli (EPEC) are a type of pathogenic E. coli that cause diarrhea, primarily in infants. They attach to the intestinal lining and disrupt normal microvilli function.
5 Must Know Facts For Your Next Test
EPEC do not produce toxins like some other pathogenic E. coli strains.
They adhere to intestinal cells using bundle-forming pili (BFP).
EPEC disrupts the intestinal cell surface by forming attaching and effacing lesions.
Common symptoms of EPEC infection include watery diarrhea and vomiting.
EPEC is typically diagnosed through stool cultures and PCR testing.
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Related terms
Escherichia coli (E. coli): A diverse group of bacteria that can be harmless or pathogenic.
Enterotoxigenic Escherichia coli (ETEC): A type of E. coli that produces toxins causing traveler's diarrhea.
Attaching and Effacing Lesions: Damage to the intestinal lining caused by certain pathogens like EPEC, leading to loss of microvilli.