Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
An enhancer is a short region of DNA that can increase the transcription of genes. It functions by providing binding sites for transcription factors and other proteins necessary for gene expression.
5 Must Know Facts For Your Next Test
Enhancers can be located upstream, downstream, or even within the genes they regulate.
They function independently of their orientation and position relative to the gene.
Enhancers contain multiple binding sites for transcription factors, which help to recruit RNA polymerase.
They play a crucial role in differential gene expression during development and in response to environmental signals.
Mutations in enhancers can lead to misregulation of gene expression, potentially causing disease.