Elephantiasis

Definition

Elephantiasis is a parasitic infection characterized by extreme swelling of the limbs and other body parts. It is most commonly caused by the filarial worms Wuchereria bancrofti, Brugia malayi, and Brugia timori.

5 Must Know Facts For Your Next Test

1. Elephantiasis results from a blockage in the lymphatic system due to filarial worms.
2. The chronic inflammation associated with elephantiasis leads to thickening of the skin and underlying tissues.
3. Humans are typically infected through mosquito bites that transfer the larvae of filarial worms.
4. Symptoms can take years to develop after initial infection, often beginning with fever and inflammation.
5. Diagnosis often involves microscopic examination of blood samples to detect microfilariae.

Review Questions

• What causes the lymphatic blockages observed in elephantiasis?
• How is elephantiasis most commonly transmitted to humans?
• What are the primary symptoms associated with chronic elephantiasis?

Related terms

Lymphatic System: A network of tissues and organs that help rid the body of toxins, waste, and other unwanted materials.

Filarial Worms: Parasitic nematodes that cause diseases such as lymphatic filariasis (elephantiasis).

Microfilariae: The larval stage of filarial worms found in human blood during an active infection.