🦠microbiology review

Ehrlichia chaffeensis

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Ehrlichia chaffeensis is a gram-negative bacterium that causes human monocytic ehrlichiosis (HME), an infection transmitted through tick bites. It primarily infects white blood cells, leading to flu-like symptoms and can be severe if untreated.

5 Must Know Facts For Your Next Test

  1. Ehrlichia chaffeensis is transmitted by the lone star tick, Amblyomma americanum.
  2. The bacterium targets monocytes and macrophages in the host immune system.
  3. Symptoms of infection include fever, headache, fatigue, muscle aches, and sometimes a rash.
  4. Diagnosis is typically confirmed through serologic tests or PCR to detect bacterial DNA.
  5. Treatment usually involves antibiotics like doxycycline; early treatment improves outcomes.

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