Edema

Definition

Edema is the abnormal accumulation of fluid in interstitial tissues, leading to swelling. It can be caused by various factors, including infections that affect the circulatory and lymphatic systems.

5 Must Know Facts For Your Next Test

1. Edema can result from increased capillary permeability due to bacterial or viral infections.
2. Inflammation often accompanies edema as part of the body's innate nonspecific host defenses.
3. Virulence factors such as toxins and enzymes from pathogens can directly or indirectly cause edema.
4. Edema in the lymphatic system indicates a disruption in lymph flow, which can be caused by microbial infections.
5. Chemical mediators like histamine and cytokines play significant roles in the development of edema during an immune response.

Review Questions

• What role do virulence factors play in the development of edema?
• How does increased capillary permeability lead to edema?
• Why is inflammation commonly associated with edema?

Related terms

Cytokines:

Signaling proteins released by cells that mediate and regulate immunity, inflammation, and hematopoiesis.

Histamine:

A compound involved in local immune responses that increases vascular permeability and leads to symptoms like swelling.

Lymphatic System:

A network of tissues and organs that help rid the body of toxins, waste, and other unwanted materials through a fluid called lymph.