🦠microbiology review

Divisome

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

The divisome is a protein complex in bacterial cells responsible for cell division. It orchestrates the formation of the septum that separates the dividing cells.

5 Must Know Facts For Your Next Test

  1. The divisome is essential for binary fission in bacteria.
  2. It includes key proteins like FtsZ, which forms a ring at the future site of division.
  3. FtsI and FtsK are other important proteins involved in peptidoglycan synthesis and chromosome segregation, respectively.
  4. The divisome assembles at the mid-cell after DNA replication is nearly complete.
  5. Mutations in divisome components can lead to cell division defects or failure.

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