Dapsone

Definition

Dapsone is an antibiotic commonly used to treat leprosy and certain bacterial infections. It works by inhibiting bacterial synthesis of dihydrofolic acid.

5 Must Know Facts For Your Next Test

1. Dapsone is effective against Mycobacterium leprae, the bacterium that causes leprosy.
2. It is often used in combination with other antibiotics to prevent resistance.
3. Dapsone can cross the blood-brain barrier, making it useful in treating certain nervous system infections.
4. Adverse effects may include hemolytic anemia, particularly in individuals with G6PD deficiency.
5. It also exhibits anti-inflammatory properties, which can help reduce nerve inflammation.

Review Questions

Related terms

Mycobacterium leprae:

The bacterium responsible for causing leprosy.

Blood-brain barrier: A selective barrier that protects the brain from foreign substances in the blood.

G6PD deficiency: A genetic disorder that can lead to hemolytic anemia when exposed to certain drugs like dapsone.