Complementary strand
from class: Microbiology Definition A complementary strand is the sequence of DNA that is formed during replication, matching the original template strand according to base-pairing rules. Each base pairs with its specific partner: adenine (A) with thymine (T), and cytosine (C) with guanine (G).
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Predict what's on your test 5 Must Know Facts For Your Next Test Complementary strands ensure accurate DNA replication by following strict base-pairing rules. The enzyme DNA polymerase is responsible for synthesizing the complementary strand during replication. Each new DNA molecule consists of one original strand and one newly synthesized complementary strand, following the semi-conservative model. Hydrogen bonds form between complementary bases: A-T pairs have two hydrogen bonds, while C-G pairs have three. Errors in forming complementary strands can lead to mutations if not corrected by repair mechanisms. Review Questions What are the base-pairing rules for forming a complementary DNA strand? Which enzyme is primarily responsible for synthesizing the complementary strand during DNA replication? How do hydrogen bonds contribute to the stability of the DNA double helix?
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