Coenzyme Q

Definition

Coenzyme Q (also known as ubiquinone) is a lipid-soluble molecule found in the mitochondria, essential for aerobic cellular respiration. It plays a crucial role in the electron transport chain, facilitating ATP production.

5 Must Know Facts For Your Next Test

1. Coenzyme Q is vital for the electron transport chain, transferring electrons between complexes I/II and III.
2. It helps maintain cellular energy levels by participating in ATP synthesis.
3. Deficiencies or dysfunctions in Coenzyme Q can lead to various mitochondrial diseases.
4. Certain antimicrobial drugs can inhibit Coenzyme Q, disrupting bacterial respiration and potentially leading to bacterial cell death.
5. Supplementation of Coenzyme Q is sometimes used to mitigate side effects of statins, which can lower its levels.

Review Questions

• What role does Coenzyme Q play in the electron transport chain?
• How might antimicrobial drugs that target Coenzyme Q affect bacterial cells?
• Why is Coenzyme Q supplementation considered for patients on statin therapy?

Related terms

Electron Transport Chain: A series of protein complexes located in the mitochondrial membrane that transfer electrons and produce ATP.

ATP (Adenosine Triphosphate): The primary energy carrier in all living organisms' cells.

Mitochondrial Diseases: Disorders caused by dysfunctional mitochondria due to mutations affecting mitochondrial function.