Clarithromycin

Definition

Clarithromycin is a macrolide antibiotic used to treat various bacterial infections, including those affecting the gastrointestinal tract. It works by inhibiting protein synthesis in bacteria, thereby stopping their growth.

5 Must Know Facts For Your Next Test

1. Clarithromycin is effective against Helicobacter pylori, a common cause of peptic ulcers and gastritis.
2. It is often used in combination with other medications, such as proton pump inhibitors and additional antibiotics, for the treatment of H. pylori infections.
3. Common side effects include gastrointestinal disturbances like nausea, diarrhea, and abdominal pain.
4. Clarithromycin has a broad spectrum of activity but is particularly potent against Gram-positive bacteria and some Gram-negative bacteria.
5. Resistance to clarithromycin can develop through mutations in bacterial ribosomal RNA.

Review Questions

Related terms

Macrolide Antibiotics: A class of antibiotics that includes clarithromycin and works by inhibiting protein synthesis in bacteria.

Helicobacter pylori:

A type of bacteria commonly linked to stomach ulcers and chronic gastritis.

Proton Pump Inhibitors: Medications that reduce stomach acid production, often used alongside antibiotics like clarithromycin to treat H. pylori infections.