Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Cholesterol is a waxy, fat-like substance found in all cells of the body. It is essential for making hormones, vitamin D, and substances that help digest foods.
5 Must Know Facts For Your Next Test
Cholesterol is a key component of cell membranes in eukaryotic cells, providing structural integrity and fluidity.
In microbial biochemistry, cholesterol can influence the function and permeability of cellular membranes.
Certain antimicrobial drugs target pathways involved in cholesterol synthesis to disrupt microbial cell functions.
High levels of cholesterol in human hosts can affect drug efficacy by altering membrane properties.
Sterols like cholesterol are found predominantly in eukaryotes but not in most prokaryotes.
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Related terms
Lipid: A broad group of naturally occurring molecules that include fats, waxes, sterols (like cholesterol), fat-soluble vitamins (A, D, E, K), monoglycerides, diglycerides, triglycerides, phospholipids, and others.
Sterol: A subgroup of steroids with a hydroxyl group at the C3 position; includes important compounds like cholesterol.
Antimicrobial Drug: Substances used to kill or inhibit the growth of microorganisms; they can target various microbial structures or metabolic pathways.