🦠microbiology review

CD4 T cells

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

CD4 T cells are a type of white blood cell that play a crucial role in the immune system by helping to coordinate the body's response to infections. They are also known as helper T cells and are essential in fighting off both viral and bacterial infections.

5 Must Know Facts For Your Next Test

  1. CD4 T cells are targeted and destroyed by HIV, leading to weakened immune function.
  2. They assist other immune cells by releasing cytokines, which help direct the immune response.
  3. A healthy CD4 count ranges from 500 to 1,500 cells per cubic millimeter of blood.
  4. Low CD4 counts increase susceptibility to opportunistic infections.
  5. Antiretroviral therapy (ART) can help maintain higher levels of CD4 T cells in HIV-positive individuals.

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