Carcinogenesis

Definition

Carcinogenesis is the process by which normal cells are transformed into cancer cells. It involves a series of mutations and changes in cellular behavior that lead to uncontrolled cell growth.

5 Must Know Facts For Your Next Test

1. Carcinogenesis often involves mutations in genes that regulate cell division and apoptosis.
2. Antimicrobial drugs such as antibiotics can sometimes induce carcinogenic effects through DNA damage.
3. Some antimicrobial agents are evaluated for their potential to cause carcinogenesis during drug development.
4. Understanding the mechanisms of carcinogenesis helps in developing drugs that minimize cancer risk while treating infections.
5. Certain antimicrobial drugs inhibit enzymes or pathways also involved in preventing carcinogenesis.

Review Questions

• What role do gene mutations play in carcinogenesis?
• How can some antimicrobial drugs contribute to the process of carcinogenesis?
• Why is it important to evaluate antimicrobial agents for their potential to cause cancer?

Related terms

Apoptosis: A form of programmed cell death essential for removing damaged or unwanted cells.

Mutagenesis: The process by which genetic information is changed, resulting in a mutation.

Oncogene: A gene that has the potential to cause cancer when mutated or expressed at high levels.