key term - BSL-3 microbe

Definition

A BSL-3 microbe is a pathogen that requires Biosafety Level 3 containment due to its potential to cause serious or potentially lethal disease through inhalation. These microbes necessitate strict laboratory practices and specialized equipment to prevent airborne transmission.

5 Must Know Facts For Your Next Test

1. BSL-3 microbes are associated with severe respiratory infections that can be fatal if inhaled.
2. The containment measures for BSL-3 include controlled access, use of personal protective equipment (PPE), and ventilated workspaces.
3. Examples of BSL-3 microbes include Mycobacterium tuberculosis and SARS-CoV-2.
4. Infection with a BSL-3 microbe often requires medical intervention and can pose significant public health risks.
5. Research on BSL-3 pathogens must be conducted in specially designed laboratories equipped with HEPA filtration systems.

Review Questions

• What level of biosafety is required for handling microbes that can cause serious respiratory diseases through inhalation?
• Name two examples of BSL-3 pathogens relevant to respiratory system infections.
• What specific laboratory practices are essential when working with BSL-3 microorganisms?

Related terms

Biosafety Level (BSL): A set of biocontainment precautions required to isolate dangerous biological agents in an enclosed laboratory facility.

HEPA Filtration System: High-efficiency particulate air filters used to remove airborne particles, crucial in maintaining air purity in BSL-3 labs.

Personal Protective Equipment (PPE): Specialized clothing or equipment worn by laboratory personnel to protect against harmful biological agents.