🦠microbiology review

Bacillus subtilis

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Bacillus subtilis is a Gram-positive, rod-shaped bacterium commonly found in soil and the gastrointestinal tract of ruminants. It is known for its ability to form a tough, protective endospore, allowing it to tolerate extreme environmental conditions.

5 Must Know Facts For Your Next Test

  1. Bacillus subtilis is widely used as a model organism for studying bacterial chromosome replication and cell differentiation.
  2. It produces several antibiotics such as bacitracin which are effective against other Gram-positive bacteria.
  3. The bacterium is capable of forming biofilms, which provide increased resistance to antimicrobial agents.
  4. Bacillus subtilis can sporulate, a process where it forms endospores that can survive heat, desiccation, and chemical disinfectants.
  5. It has been genetically engineered for various industrial applications including enzyme production and biopesticides.

Review Questions

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