🦠microbiology review

B. hermsii

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Borrelia hermsii is a spirochete bacterium that causes tick-borne relapsing fever in humans. It is primarily transmitted through the bite of soft ticks from the genus Ornithodoros.

5 Must Know Facts For Your Next Test

  1. Borrelia hermsii is a significant cause of tick-borne relapsing fever in North America.
  2. The bacterium undergoes antigenic variation, which allows it to evade the host's immune system and cause recurrent fever episodes.
  3. Infections typically present with sudden high fevers, chills, headaches, muscle and joint aches, and nausea.
  4. Diagnosis can be confirmed through blood smears stained with Giemsa or Wright stain, where spirochetes can be directly observed.
  5. Treatment commonly includes antibiotics such as doxycycline or erythromycin.

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