Aspergillus

Definition

Aspergillus is a genus of mold commonly found in the environment that can cause infections, particularly in immunocompromised individuals. These fungi are known for producing conidia, which can be inhaled and lead to respiratory issues.

5 Must Know Facts For Your Next Test

1. Aspergillus species are opportunistic pathogens that primarily affect individuals with weakened immune systems.
2. The most common species causing human disease is Aspergillus fumigatus.
3. Aspergillosis can manifest in various forms, including allergic bronchopulmonary aspergillosis, invasive aspergillosis, and aspergilloma.
4. Virulence factors of Aspergillus include proteases and toxins such as gliotoxin.
5. Environmental conditions like temperature, humidity, and nutrient availability significantly influence Aspergillus growth.

Review Questions

• What are the primary virulence factors of Aspergillus?
• How does Aspergillus primarily enter the human body to cause infection?
• In what types of patients is Aspergillosis most commonly observed?

Related terms

Conidia:

Asexual spores produced by molds like Aspergillus that are dispersed through the air.

Immunocompromised Host:

An individual whose immune system is weakened or deficient, making them more susceptible to infections.

Mycoses: Infections caused by fungi.