Antigen mimicry is a phenomenon where foreign antigens share structural similarities with self-antigens, leading the immune system to mistakenly attack its own cells. This can result in autoimmune disorders.
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Antigen mimicry is a key mechanism in the development of certain autoimmune diseases.
Molecular mimicry can cause the immune system to generate cross-reactive antibodies that target both pathogens and self-tissues.
Examples of diseases associated with antigen mimicry include rheumatic fever and multiple sclerosis.
Infections by certain viruses or bacteria can trigger antigen mimicry due to shared peptide sequences with host proteins.
Research into antigen mimicry helps in understanding autoimmunity and developing therapies to prevent or mitigate autoimmune responses.
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Related terms
Autoimmune Disorder: A condition in which the immune system mistakenly attacks the body's own tissues.
Cross-Reactivity: The reaction of one antigen with antibodies developed against another antigen due to structural similarity.