Agglutination reactions are immunological tests where particles (such as bacteria or red blood cells) clump together due to the binding of antibodies. These reactions are used for detecting and identifying antigens or antibodies in a sample.
5 Must Know Facts For Your Next Test
Agglutination reactions can be used to identify bacterial pathogens in skin and eye infections by detecting specific antigens.
They are commonly employed in rapid diagnostic tests for conditions such as bacterial conjunctivitis.
The reaction is visible to the naked eye, making it a simple and quick diagnostic tool.
Agglutination can occur with either direct or indirect methods, depending on whether the antibody binds directly to the antigen or involves an additional reagent.
False positives or negatives can occur if proper controls are not included, emphasizing the need for accurate technique.