🦠microbiology review

Acute herpes labialis

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Acute herpes labialis is a viral infection caused by the herpes simplex virus type 1 (HSV-1), resulting in cold sores or fever blisters primarily around the mouth. It is highly contagious and typically reactivates during periods of stress or immunosuppression.

5 Must Know Facts For Your Next Test

  1. Herpes simplex virus type 1 (HSV-1) is the primary cause of acute herpes labialis.
  2. Transmission occurs through direct contact with infected saliva, skin, or mucous membranes.
  3. Symptoms include painful blisters or sores around the lips and mouth, often preceded by itching or tingling sensations.
  4. Reactivation of the virus can be triggered by factors such as stress, illness, sunlight exposure, and hormonal changes.
  5. Antiviral medications like acyclovir can reduce the severity and duration of outbreaks.

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