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Blood glucose levels

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Intro to Pharmacology

Definition

Blood glucose levels refer to the concentration of glucose present in the bloodstream, which is crucial for providing energy to the body's cells. Maintaining optimal blood glucose levels is essential for overall health, as both elevated and decreased levels can lead to serious health issues, including diabetes and hypoglycemia. The regulation of these levels involves hormones such as insulin, which plays a vital role in lowering blood sugar after meals, and oral hypoglycemic agents that assist in managing blood glucose for individuals with diabetes.

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5 Must Know Facts For Your Next Test

  1. Normal blood glucose levels typically range from 70 to 99 mg/dL when fasting and can rise to about 140 mg/dL two hours after eating.
  2. Insulin is released from the pancreas in response to elevated blood glucose levels, promoting the uptake of glucose by cells for energy or storage as glycogen.
  3. Oral hypoglycemic agents include various classes of drugs, such as sulfonylureas and biguanides, which work through different mechanisms to help lower blood sugar levels.
  4. Monitoring blood glucose levels is essential for individuals with diabetes to avoid complications such as neuropathy, retinopathy, and cardiovascular issues.
  5. Persistent high blood glucose levels can lead to a condition called hyperglycemia, which may result in diabetic ketoacidosis if left untreated.

Review Questions

  • How does insulin function in regulating blood glucose levels after a meal?
    • Insulin is released by the pancreas in response to increased blood glucose levels following a meal. It helps cells throughout the body absorb glucose, thus lowering the concentration of glucose in the bloodstream. This process not only provides immediate energy to cells but also promotes the storage of excess glucose as glycogen in the liver and muscle tissues for later use.
  • Discuss the role of oral hypoglycemic agents in managing blood glucose levels for people with type 2 diabetes.
    • Oral hypoglycemic agents play a critical role in managing blood glucose levels for individuals with type 2 diabetes who may not produce enough insulin or cannot effectively use it. These medications work through various mechanisms: some stimulate insulin production from the pancreas, while others improve insulin sensitivity or reduce hepatic glucose production. The choice of medication depends on the individual's specific health needs and the desired target for their blood sugar control.
  • Evaluate the long-term effects of uncontrolled blood glucose levels on overall health and wellbeing.
    • Uncontrolled blood glucose levels can lead to significant long-term health complications, such as cardiovascular disease, kidney failure, nerve damage, and vision problems like retinopathy. Chronic hyperglycemia affects nearly every organ system in the body due to damage from high sugar concentrations and resultant inflammation. Effective management through lifestyle changes, regular monitoring, and appropriate medication is crucial for reducing these risks and maintaining overall health.
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