The Wounded Knee Incident refers to the tragic confrontation on December 29, 1890, between U.S. troops and members of the Lakota Sioux tribe at Wounded Knee Creek in South Dakota, which resulted in the deaths of around 300 Lakota men, women, and children. This event marked a significant moment in U.S. history, highlighting the violent repression of Native American cultures and the broader struggles against colonialism that sparked later movements advocating for Native American rights and sovereignty.