Newton's Principia Mathematica, formally titled 'Philosophiæ Naturalis Principia Mathematica', is a seminal work published in 1687 by Isaac Newton that laid the groundwork for classical mechanics. It introduced the universal law of gravitation and the three laws of motion, which profoundly influenced not only the scientific community but also philosophical thought during the Enlightenment, fundamentally altering humanity's understanding of the physical universe.